PD-L1: expression regulation
Programmed death-ligand 1 (PD-L1), expressed on the surface SEMET of tumor cells, can bind to programmed cell death-1 (PD-1) on T cells.The interaction of PD-1 and PD-L1 can inhibit T-cell responses by decreasing T-cell activity and accelerating their apoptosis.Various cancers express high levels of PD-L1 and exploit PD-L1/PD-1 signaling to evade T